Posted in Experience, fitness, learnings, Life, Weight Loss

Avoid these night-time habits that helps you gain weight

weight

You’re not sleeping enough

New role at the office, exam time, a fulltime gamer etc. can be a reason not to sleep enough as there is something to achieve something in life. But going all the way can hurt us very badly in terms of health.

  • Metabolism slows down, as the digestion is at its peak when we sleep and when we don’t it ads to body fat.
  • Sleeping less means more time in your senses and hence more eating.
  • You are already tiered and hence you will not be able to work out well thus you lose on losing out body fat.
  • It increases your cortisol level. “Cortisol is made by the adrenal glands. Cortisol levels go up when the pituitary gland releases another hormone called adrenocorticotropic hormone (ACTH). Cortisol has many functions. It helps the body use sugar (glucose) and fat for energy (metabolism), and it helps the body manage stress.”
  • Going to bed past midnight makes you gain more fat because it’s not the natural body cycle.
  • You will want to eat something early in the morning.

Hence let’s make a habit of increasing our sleeping hours to a minimum of 6-8 depending on your day. Go to sleep as soon as you feel sleepy. If you feel upbeat by the end of your day, try to include some physical exercises.

You overeat at dinner and sleep right after the meal

Fight with someone you love, stress at work, party etc. a lot of things can make you eat a lot of un-necessary things at dinner. Now, this is bad as you are going to sleep after that without much of physical activity.

  • The digestion of heavy food at night happens slowly as it takes more time to break down the complex things that just went down your throat.
  • Watching your favorite soap diverts your mind and makes you eat more so just one thing at a time.
  • Just sleeping after meals will get more fat accumulated and you can have digestive problems

Hence, having a light dinner high in proteins and fibers in a small plate talking to family and friends. Then take a walk or set the home right so that you have at least 1.5-hour gap before sleeping.

Having an oil filled, spicy and fried dinner

Cannot resist those French fries, burgers, etc. at a party. Just remember that you don’t have time to burn them off.

  • Too many calories mean more fat accumulated as you will mostly hit bed after that
  • Spicy food leads to poor digestion and increases in heart rates which are not good for one’s health.
  • Uneasiness and not a great sleep are some of the consequences to face.

Spicy food is good for speeding up your metabolism. Eat it, if you like it — maybe just not at night. For dinner, you can have smoothies or fresh fruit, all kinds of salads or high-protein foods. But in small portions, of course!

 

You have a sweet tooth, do a lot of snacking at dinner time, alcohol and love eating it before going to bed

Chocolates, Shakes, Sweets can be a breaking point for many. Many of us broke our resolution because of this.

  • White sugar and flour transform into fat cells if not burned and hence creates that belly that you have, yes right there!!
  • Snacking leads to over eating and you consume empty calories
  • You then become hyperactive and will not be able to sleep as the body now has more energy.

For dessert, have some fruit. It’s like healthy candy that won’t hurt your waist. This solves your sweet and snacking problem

Eating less dinner is great and helps loose

Oh!! Yes, today I skipped dinner, I have to burn less and will lose weight is the concept many people have in mind.

  • It doesn’t help you lose much weight because skipping meals slows your metabolism and hence helps in accumulation of fat.
  • It aids more hunger to the next meal that you will have and you, in turn, end up eating more. It can cause anxiety and you will have the problem in concentrating.
  • You lose muscle tissue, and your skin gets loose which then becomes impossible to lose.

Even if you don’t have time for a decent lunch or dinner, at least try to eat a piece of fruit which helps you to get rid of all the things said above.

 Can’t live without checking my phone

She/ He messaged me and I must reply otherwise it will become a big fight and we stay glued to the screens.

  • Blue light, emitted by those gadgets, affects health and sleep., Radio frequency waves also cause sleep deprivation and thus creates a lot of problems

Turn devices off at least one hour before bed. Read a book or listen to relaxing music instead.

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Posted in customer service, Startups

Customer Support – DNA of a Company which builds a Brand

Customer Service

The team which is always there for the customers, whether its Holi or Diwali or just another day. We are the “Customer Support”. We make sure that our customers are not getting affected at any point, all days of the year.
A typical day of ours starts with team logging in all the support channels where the customer reaches out, which can be Chat, Emails, Calls etc. We spend most of the time answering to the inbound queries and issues of the customers. During the day, we also work with other departments to deal with different type of customer issues we get.
We have a range of problem thrown at us during the day. Right from an easy how to question to a difficult objection handling on a policy or product. Each day for us is a rollercoaster ride right from start to the finish. We have best of our days where we satisfy a customer with all his/ her queries and we also have worst of our days when many customers are dissatisfied with the answers we have for them.
The best part of our job is to be able to see things from a customer’s perspective and then help other departments in the improvement of products and services. The worst part of our job is delivering decisions on problems to the customers which are beyond our control, although we may sometimes know that the customer is not wrong. But these are business decisions where our control is minimum.
Multitasking is in our blood, we eat, work, have fun on the floor and all of this at one time. We have snack’s day, pot luck and make sure we have our part of the fun. Sometimes our leaders also join us and we enjoy their company a lot, though we would like to have some more of their time but we understand.
We are like an invisible backbone which is always there and supports but no one sees it from outside and realize its importance. But once people know what it takes to be here they never forget the importance of CUSTOMER SUPPORT. It is the voice of the company which show’s its DNA and is one of the most important elements of the brand building.

Lohith from the team says “Being in support is about saving emotion, no matter what kind of day we  have have been through all that  we do is greet our  customers with smile,it’s not about being phelgmatic it’s about being passionate”. 
Customer service is not only about the people in the frontline, it’s about the company as a whole all the departments of a company collectively define how your customer service is.
Please join us and experience what our customers go through day in and out and be their voice.

Posted in learnings, Research

Do you have a Dream?

Holidays are the best days to tick off some items from your to-do list. One of them was the movie called “The Bucket List” on a friend’s suggestion, I regret not having watched it all this while. It’s a much watch for anyone.

After watching, I noted down my own personal bucket list and here it is:

  • Himalayan ranges trekking in 2017
  • Sending Mom and Dad on a Euro Trip by 2017 end
  • Gifting my sister an architectural kit

But this got me wondering. Edward Cole was the billionaire, most people are not. He was terminally ill, so ironic as it is, time was not a constraint. Or was it?

The Bucket List

I imagine the world where If I have a dream if there is anything I want to do, I should be able to do it. I started wondering what keeps people from achieving some of these dreams? What keeps them from ticking off items from their personal bucket lists?

I made a short survey here to understand some of these things:

https://docs.google.com/forms/d/e/1FAIpQLSdlhznZkIvB31R6s0swOp-RjoS2ShXme1kReox_m62XpkPENg/viewform

I will then share my learnings in next series of article on the same.

 

Posted in Entrepreneurship, Marketing, Research, Startups

Basics of Digital Marketing – Social Media Marketing, SEO, Google Adwords

I started learning about digital marketing while I was still in college. There was  so much to read on the web that I generally got confused as to what should I read and what not. Hence, now as I have gone through the basics of digital marketing and have applied it in many situations here is a capsule of information which will give you a basic understanding of the concepts. This is taken from multiple sources so that it gives the most complete knowledge of the concepts.

Google AdWords –

Google AdWords is Google’s advertising system in which advertisers bid on certain keywords in order for their clickable ads to appear in Google’s search results. Since advertisers have to pay for these clicks, this is how Google makes money from search.

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Basic Process

How to advertise with Google AdWords?

Businesses can advertise on Google by opening a Google AdWords account.

How does AdWords bidding work?

The actual position of your ad is determined by your ad rank (Maximum Bid * Quality Score). The highest ad rank gets the 1st ad position. Your actual CPC (Cost per Click) will be determined by the ad rank of the next highest ad below you divided by your Quality Score. The only exception to this rule is when you are the only bidder or the lowest bid in the AdWords auction; then you pay your maximum bid per click! AdWords bidding heavily penalizes advertisers who bid with low-quality scores. Conversely, those with high-Quality Scores get higher ad ranks and lower CPC.

How many times does a Google auction run?

The auction gets run billions of times each month. The results are such that users find ads that are relevant to what they’re looking for, advertisers connect with potential customers at the lowest possible prices.

How does the Google auction work?

Once a query is made on Google, the search engine processes the request and runs the auction which will then determine the ad positions and each advertiser’s CPC.

How do you enter a Google auction?

Your ads are eligible to be entered into an auction whenever you’re bidding on keywords relevant to the user’s search query. Your bids, Quality Score, and relevance will come into play in determining whether your ad qualifies to display on the SERP (Search Engine Result Page).

What gets entered into a Google auction?

Once advertisers identify keywords they want to bid on, Google then enters the keyword from your account that it deems most relevant into the auction with the maximum bid you’ve specified as well as the associated ad.

What is CPC?

CPC, or cost per click, is the amount an advertiser pays each time someone clicks on their AdWords ad.

How does CPC work?

Your CPC is determined by the competitiveness of your keywords, your maximum bids, and your Quality Scores.

What is the average cost per click?

The average amount you spend each time a searcher click on your advertisement.

What is Google Quality Score?

This is a metric Google uses to determine how relevant and useful your ad is to the user, based primarily on your ad’s CTR, keyword relevance, and the quality of your landing page. The higher your Quality Score, the better: high-Quality Score keywords will save you money and earn you better ad rankings.

How does Google determine what you pay?

The price paid by the advertiser is determined by a number of clicks that the company’s advertisement receives.

What is Google ad rank?

Google ad rank is the position of the company’s advertisement on the search engine page based on a combination of the company’s maximum bid and quality score.

Ad rank vs. Quality score

The ad rank is more significant to an advertiser because it determines the how high on the page the advertisement will be displayed. Quality score, on the other hand, is determined by the relevance and usefulness to the searcher and is only a portion of the advertisement positioning process.

Quality score vs. CPC

Quality score and CPC are important because they collective determine the positioning of the advertisement on the search engine results page.

What is ad position in AdWords?

Ad position is the position on the search engine page results where the advertisement appears in relation to all of the other advertisements.

What is Actual CPC?

Actual CPC is the amount an advertiser pays each time a searcher clicks on their advertisement; this number varies depending on the other advertisers in the auction and is always lower than the maximum bidding price.

How does AdWords calculate Actual CPC

Actual CPC is determined by dividing the ad rank of the competitor below them (ad rank to hit) by quality score plus $.01.

What are alternative bidding methods?

Alternative bidding methods include CPM and CPA.

What is CPM bidding?

CPM bidding is based on impressions and can be used alongside CPC bidding.

CPC vs. CPM

CPC is the cost for an advertisement based on how many clicks it receives whereas CPM is the cost for an advertisement based on how many impressions it picks up. Both methods can be used simultaneously.

What are AdWords keywords?

Keywords in AdWords are the words and phrases that advertisers bid on, in hopes that their advertisements will appear on the search engine results page (SERP) when people are searching for those products or services. For example, if you are booking doctor appointments online, you might bid on keywords like “Online doctors” and “dentist in Bangalore.” Keyword research is the process of using tools and data to determine which keywords are most likely to drive relevant traffic to your ads and your site.

How does the Google display network work?

The Google Display Network or GDN is a very large network of sites that allow Google to place display advertisements, which reach over 90% of all Internet users! Advertisers generally find that Display Network clicks are less costly than those on the search network. And depending on your targeting methods, the CTR’s can be high and the CPA’s low.

What is an ad group in Google AdWords? How do ad groups work?

An ad group is a container for your AdWords advertisements, keywords, and landing pages. Google tends to reward advertisers who create AdWords campaigns with tightly structured ad groups. It’s important not to dump all your keywords into the same ad group, but to organize your keywords into themes.

What is ad relevance in AdWords?

Ad relevance is a measure of how related the keyword you’re bidding on is to your advertisements as well as how much your keywords match the message of your ads and landing pages. Higher ad and keyword relevance can improve your click-through rates and Quality Scores.

I advertise on Google. How am I doing?

The easiest way to see how you’re doing at Google PPC is to benchmark your PPC performance against similar advertisers in your industry and spend range.

Search Engine Optimization –

Search engine optimization is the act of improving the visibility of your site or page within a search engine results page through organic methods. This can be done by using search keywords within your content so that a search engine can find and display your site faster and with more accuracy. Site authority and your link profile also play a role in your search engine rankings. Some of the factors are

  • Keyword Quality
  • Landing page content
  • Website Backend – title tag and meta description
  • Links in from other websites
  • Social media impact – sharing and buzz about company
  • Cross Linking the website pages deems it relevant

SEO considers how search engines work, what people search for, the actual search terms or keywords typed into search engines and which search engines are preferred by their targeted audience. Optimizing a website may involve editing its content, HTML and associated coding to both increase its relevance to specific keywords and to remove barriers to the indexing activities of search engines. Promoting a site to increase the number of backlinks, or inbound links are SEO tactic.

Google offers Google Webmaster Tools, for which an XML Sitemap feed can be created and submitted for free to ensure that all pages are found, especially pages that are not discoverable by automatically following links.

Search engine optimization is the process of optimizing web pages and their content to be easily discoverable by users searching for terms relevant to your website. The term SEO also describes the process of making web pages easier for search engine indexing software, known as “crawlers,” to find, scan, and index.

Why Should You Care About SEO?

Billions of searches are conducted online every single day. This means an immense amount of specific, high-intent traffic.

Many people search for specific products and services with the intent to pay for these things. These searches are known to have commercial intent, meaning they are clearly indicating with their search that they want to buy something you offer.

What Actually Works for Driving Traffic from Search Engines?

It’s important to note that Google is responsible for the majority of the search engine traffic in the world.

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So how does Google determine which pages to return in response to what people search for?

Google’s algorithm is extremely complex, but at a high level:

  • Google is looking for pages that contain high-quality, relevant information relevant to the searcher’s query.
  • Google’s algorithm determines relevance by “crawling” (or reading) your website’s content and evaluating (algorithmically) whether that content is relevant to what the searcher is looking for, based on the keywords it contains and other factors (known as “ranking signals”).
  • Google determines “quality” by a number of means, but a site’s link profile – the number and quality of other websites that link to a page and site as a whole – is among the most important.

Increasingly, additional ranking signals are being evaluated by Google’s algorithm to determine where a site will rank, such as:

  • How people engage with a site (Do they find the information they need and remain on the site, or do they “bounce” back to the search page and click on another link? Or do they just ignore your listing in search results altogether and never click-through?)
  • A site’s loading speed and “mobile friendliness”
  • How much unique content a site has (versus “thin” or duplicated, low-value content)

There are hundreds of ranking factors that Google’s algorithm considers in response to searches, and Google is constantly updating and refining its process to ensure that it delivers the best possible user experience.

Keyword Research & Keyword Targeting Best Practices

The first step in search engine optimization is to determine what you’re actually optimizing for. This means identifying terms people are searching for, also known as “keywords,” that you want your website to rank for in search engines like Google.

There are several key factors to take into account when determining the keywords you want to target on your site:

  • Search Volume – The first factor to consider is how many people are actually searching for a given keyword. The more people there are searching for a keyword, the bigger the potential audience you stand to reach. Conversely, if no one is searching for a keyword, there is no audience available to find your content through search.
  • Relevance – A term may be frequently searched for, but that does not necessarily mean that it is relevant to your prospects. Keyword relevance, or the connection between content on a site and the user’s search query, is a crucial ranking signal.
  • Competition – Keywords with higher search volume can drive significant amounts of traffic, but competition for premium positioning in the search engine results pages can be intense.

Once you’ve taken the time to understand your prospects, have looked at the keywords driving traffic to your competitors and related sites, and have looked at the terms driving traffic to your own site, you need to work to understand which terms you can conceivably rank for and where the best opportunities actually lie.

On-Page Optimization in brief

Once you have your keyword list, the next step is actually implementing your targeted keywords into your site’s content. Each page on your site should be targeting a core term, as well as a “basket” of related terms.

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Let’s look at a few critical, basic on-page elements you’ll want to understand as you think about how to drive search engine traffic to your website:

Title Tags

The title tag is not your page’s primary headline. The headline you see on the page is typically an H1 (or possibly an H2) HTML element. The title tag is what you can see at the very top of your browser, and is populated by your page’s source code in a meta tag:

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Meta Descriptions

While the title tag is effectively your search listing’s headline, the meta description (another meta HTML element that can be updated in your site’s code, but isn’t seen on your actual page) is effectively your site’s additional ad copy. Here’s an example of a real world meta description showing in search results:

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Body Content

The actual content of your page itself is, of course, very importantThat said, Google has been increasingly favoring certain types of content, and as you build out any of the pages on your site, there are a few things to keep in mind:

  • Thick & Unique Content
  • Engagement
  • “Sharability”

URL Structure

Your site’s URL structure can be important both from a tracking perspective (you can more easily segment data in reports using a segmented, logical URL structure), and a shareability standpoint (shorter, descriptive URLs are easier to copy and paste and tend to get mistakenly cut off less frequently). Again: don’t work to cram in as many keywords as possible; create a short, descriptive URL.

Schema & Markup

Finally, once you have all of the standard on-page elements taken care of, you can consider going a step further and better helping Google (and other search engines, which also recognize schema) to understand your page.

Schema markup does not make your page show up higher in search results (it’s not a ranking factor, currently). It does give your listing some additional “real estate” in the search results, the way ad extensions do for your AdWords ads.

In some search results, if no one else is using schema, you can get a nice advantage in click-through rate by virtue of the fact that your site is showing things like ratings while others don’t. In other search results, where everyone is using schema, having reviews may be “table stakes” and you might be hurting your CTR by omitting them:

 

Social Media Marketing

Social media marketing programs usually center on efforts to create content that attracts attention and encourages readers to share it across their social networks. The resulting electronic word of mouth (eWoM) refers to any statement consumers share via the Internet (e.g., websites, social networks, instant messages, news feeds) about an event, product, service, brand or company.

Social media marketing can help with a number of goals, such as:

  • Website traffic
  • Conversions
  • Brand awareness
  • Creating a brand identity and positive brand association
  • Communication and interaction with key audiences
  • Only by establishing your goals can you measure your social media ROI.

Factors to be kept in mind for SMM

Planning – As discussed previously, building a social media marketing plan is essential. Consider keyword research and brainstorm content ideas that will interest your target audience.

Content is King — Consistent with other areas of online marketing, content reigns king when it comes to social media marketing. Make sure you are offering valuable information that your ideal customers will find interesting. Create a variety of content by implementing social media images, videos, and infographics in addition to classic text-based content.

Consistent Brand Image — using social media for marketing enables your business to project your brand image across a variety of different social media platforms. While each platform has its own unique environment and voice, your business’ core identity should stay consistent.

Links — it’s also great to link to outside articles as well. If other sources provide great, valuable information you think your target audience will enjoy, don’t be shy about linking to them. Linking to outside sources improves trust and reliability, and you may even get some links in return.

Track Competitors — it’s always important to keep an eye on competitors—they can provide valuable data for keyword research, where to get industry-related links and other social media marketing insight. If your competitors are using a certain social media marketing technique that seems to be working for them, do the same thing, but do it better!

Measure Success with Analytics —you can’t determine the success of your social media marketing strategies without tracking data.

Various platform for SMM

Facebook’s casual, friendly environment requires an active social media marketing strategy that begins with creating a Facebook Business Fan Page.  You will want to pay careful attention to layout, as the visual component is a key aspect of the Facebook experience. Social media marketing for business pages revolves around furthering your conversation with audiences by posting industry-related articles, images, videos, etc.

Google+ is the new Facebook competitor, and it promotes the same fun, casual atmosphere. On Google+, you can upload and share photos, videos, links, and view all your +1s. Also take advantage of Google+ circles, which allow you to segment your followers into smaller groups, enabling you to share information with some followers while barring others. For example, you might try creating a “super-fan” circle, and share special discounts and exclusive offers only with that group.

Pinterest is the latest in social media marketing trends. Pinterest’s image-centered platform is ideal for retail, but anyone can benefit from using Pinterest for social media purposes.

Pinterest allows small businesses to showcase their own product offerings while also developing their own brand’s personality with some unique pinboards.

Twitter is the social media marketing tool that lets you broadcast your updates across the web. Follow tweeters in your industry or related fields, and you should gain a steady stream of followers in return.

Mix up your official-related tweets about specials, discounts, and news updates with some fun and quirky tweets interspersed.

LinkedIn is one of the more professional social media marketing sites. LinkedIn Groups is a great venue for entering into a professional dialog with people in similar industries and provides a place to share content with like-minded individuals.

YouTube is the number one place for creating video content, with can be an incredibly powerful social media marketing tool. Many businesses try to create video content with the aim of having their video “go viral,” but in reality, those chances are pretty slim.

Reddit, or similar social media platforms such as Stumble Upon or Digg, are ideal for sharing compelling content. With over 2 billion page views a month, Reddit has incredible social media marketing potential, but marketers should be warned that only truly unique, interesting content will be welcomed. Posting on Reddit is playing with fire—submit spams or overtly sales-focused content and your business could get berated by this extremely tech-savvy community.

Using social media in marketing does more than improving site traffic and help businesses reach more customers; it provides a valuable venue for better understanding and learning from your target audiences. Hopefully, this guide has helped you better understand how using social media for marketing can improve your business.

Hope tis helped you in getting the baisc grasp of things. If you think this was beneficial, please share it with your peers who may be interested.

Posted in Research

Why do users generally uninstall Apps ???

Let us first look at some background on the facts about the internet and smartphone usage in the country. Following that, we will try to understand the reason responsible for an app to stay on the smartphone device.

  • There are about 320 Mn total internet users in the country (which include Mobile and other users). (
  • Out of the total, about 200 Mn (16% of total mobile connection subscribers) are mobile internet users. Out of which 150 Mn are urban and 50 are rural mobile users.
  • The total unit of smartphones users is 160 Mn (mobiles) + 2.7Mn (tab).
  • Out of the total smartphones, 65% of smartphones are of less than 10000.
  • The majority of Smartphone density lies in Maharashtra (23.8%), Delhi (15.8%), WB (14.1%), and Karnataka (5.8%).
  • 60% of the smartphone sold are 3G enabled.
  • 70% of the users of smartphones are less than 30 years of age.
  • The male-female ratio for the use of smartphones is 60:40.
  • The average specifications for a smartphone in India are –
    • 1GB RAM
    • 4-8GB Internal storage and extendable
    • Dual core and Quad core processor
    • Android
    • 10-15 Apps come inbuilt in the mobile phone which cannot be installed which uses a specified internal storage and RAM
  • The apps which are generally present in and average phone are –
    • Facebook – 200Mb
    • Chrome – 60Mb
    • WhatsApp – 80-100Mb
    • Flipkart/Snap-Deal/Amazon/ Myntra – 40-60Mb
    • Gmail – 20Mb
    • Music App – 50-80Mb
    • Games – 200-600Mb
    • Ola/Uber – 40-60Mb
    • Mobile Banking Apps – 20Mb
    • Google Now and Google Play services – 300-500Mb
    • Other google Apps (Maps, Hangout etc.) – 500-700Mb
    • Other basic Apps – 100-300Mb

Total it comes to around 2-3Gb for Apps then the people have their Music and Photos and other document data. (http://www.bgr.in/news/top-10-internet-browsing-trends-of-indian-smartphone-users/) (Digital @ Bharat by BCG India)

  • In general for a downloaded app to stay in phone it should have following utilities –
    • Keeping audience engaged or users lose interest
    • Should not eat much space on the device
    • Offers i.e. incentivising the app usage
    • Reoccurring Functionality
    • No continuous push notifications

app uninstall parameters

(http://www.forbes.com/sites/ciocentral/2013/11/21/why-people-uninstall-apps/)

  • In general, following factors are contributing to its high uninstall rates –
    • Usability only when of need
    • No engagement with users as of now
    • No offers and incentives to keep the app
    • It eats space on the device
    • Can be downloaded when needed
Posted in Research

Genome Mapping – The FUTURE

What is a Genome?

A genome is all the genetic material of a living thing. It is the entire set of hereditary instructions for building, running, and maintaining an organism, and passing life on to the next generation. The relation of Genome with DNA is given as under.

Genome mapping

Each species on earth has its own distinctive Genome and even within species, it’s different.

What is genome sequencing?

Genome sequencing is like “decoding,” but a sequence is still very much in code. In a sense, a genome sequence is simply a very long string of letters in a mysterious language.

So sequencing the genome doesn’t immediately lay open the genetic secrets of an entire species. Even with a rough draft of the human genome sequence in hand, much work remains to be done. Scientists still have to translate those strings of letters into an understanding of how the genome works: what the various genes that make up the genome do, how different genes are related, and how the various parts of the genome are coordinated.

What is Genome Mapping?

A genome map helps scientists navigate around the genome. Like road maps and other familiar maps, a genome map is a set of landmarks that tells people where they are and helps them get where they want to go. Often, genome maps are used to help scientists find new genes and the genes due to which the disease are passed to generations.

What does a genome map look like?

Most everyday maps have length and width, latitude and longitude, like the world around us. But a genome map is one-dimensional—it is linear, like the DNA molecules that make up the genome itself. A genome map looks like a straight line with landmarks noted at irregular intervals along it, much like the towns along the map of a highway. The landmarks are usually inscrutable combinations of letters and numbers that stand for genes or other features—for example, D14S72, GATA-P7042, and so on.

What is the difference between a genome map and a genome sequence?

Both are portraits of a genome, but a genome map is less detailed than a genome sequence. A sequence spells out the order of every DNA base in the genome, while a map simply identifies a series of landmarks in the genome. But both are independent of each other.

In other cases, the landmarks on a map are DNA sequences, and mapping is the cousin of sequencing. For example, consider the following sequence:

genome-1

A map of that sequence might look like this:

genome-2
In general, particularly for humans and other species with large genomes, creating a reasonably comprehensive genome map is quicker and cheaper than sequencing the entire genome. Simply put, mapping involves less information to collect and organize than sequencing does.On this map, GCC is one landmark; CCCC is another. In the corresponding sequence, each base is a landmark. In other words, the sequence is simply the most detailed possible map.

Many animal “genome projects” now underway, such as those that focus on the dog and the horse, aim to map the genomes of these species. This will help scientists learn more about the biology of these species, without the enormous resources required when sequencing a genome.

By contrast, studying the human genome is actually a two-pronged effort, aiming at both a comprehensive genome map and a complete genome sequence. Advances in sequencing help the mapper move ahead, and advances in mapping help the sequencers make progress. These efforts are closely linked but not exactly the same thing.

Why map a genome if we are going to sequence it anyway?

One reason is that a map can actually help you sequence the genome. If you’re sequencing a genome with the clone-by-clone method, you need a map to decide where each clone belongs in the genome. The more detailed and correct your map, the easier it is to snap those pieces of a genomic jigsaw puzzle into place. For the most part, scientists can’t look at a sequence and see immediately which parts are genes or other interesting features, and which parts are “junk.” But the landmarks on a genome map give clues about where the important parts of the genome sequence can be found.

What are genome maps used for?

Genome maps help scientists find genes, particularly those involved in human disease. This process is much like a scientific game of hot and cold. Scientists study many families affected by a disease, tracing the inheritance of the disease and of specific genome landmarks through several generations. Landmarks that tend to be inherited along with the disease are likely to be located close to the disease gene and become “markers” for the gene in question.

Once they have identified a few such markers, scientists know the about location of the disease gene. In this way, they narrow down their search from the entire 3-billion-base-pair genome to a region of the genome a few million base pairs long.

Next, they look for genes in that part of the genome and study the genes one by one to learn which one is involved in the disease. For example, they might look for a gene that has a different sequence in people with the disease than it does in healthy people. Or they might look for a gene with a function that could be related to the disease.

In the future, researchers hope that more detailed genome maps will help them find genes faster, leading them straight to each gene the way you can look at a road map and find the sequence of streets that will take you exactly where you want to go. A more detailed map would also help scientists study complex human diseases and traits that involve many genes—for example, cancer, heart disease, and personality. Finally, genome maps enable scientists to compare the genomes of different species, yielding insights into the process of evolution.

What is the research going on in this area?

  • Finding a cure to the disease like cancer etc.
  • Increasing the human strength to machines
  • Molecular Medicine
  • Studying Human Evolution
  • Biofuels and Energy Applications(Harnessing power of bacteria)
  • Bioprocessing & Forensics etc.
Posted in Experience, Life

Experience of living in a shared flat

Someone rightly said always choose the people you live with, not the place ~Anonymous

living together in a shared flat

I started living in a shared setup when I started my first job. I had an option to either take a PG or live in a shared flat by SimplyGuest. I chose to take the flat which for me was the better choice.

There are pros and cons to living in a flat as opposed to a PG. One of the biggest advantages of living in a flat is the privacy. I love my privacy and independence. There are some days where I just want to be alone and not have to deal with other people, and being in a flat allows me to do this.

There are some weeks we barely see each other. Everyone had work/ family schedules etc. We had dinner/drinks together at least twice a week to iron out anything that anyone was annoyed about. And we used to have parties all together every month and would all invite our friends, nothing out of hand, just some fun.

Additionally, I don’t have to eat at a specific time If I wanted to I could go out and get Taco Bell at 7 o’clock and eat it while watching Netflix in my room. I don’t feel bad about not eating with my flatmates. We are all on different schedules so we eat when we can. You always have the different kind of cuisines cooked at your place, no Aloo always. Which is a huge relief as we get to eat what we want to and not follow a menu or hog outside food. We don’t have to wait for eating on a timing. We always have food in our fridge courtesy one of my flatmate who is a foodie and hence we always have supplies to enjoy a weekday or a weekend evening.

One of the best things about sharing a flat is that there is absolutely no need to introduce my ‘friends’ as cousins to be with them for some time or trying hard to find a place to do so. After shifting into a shared flat by SimplyGuest I have been able to spend time with my friends and enjoy my evenings.

We have a TV in our flat and hence all of us has our share of time on TV and there is no need to do a real-life drama to watch TV. We also have a PS4 and hence we enjoy all the stuff together.

Sharing things with flatmate is quite easy as the trust level is way high then living in any other setup and hence I save a lot of money on the one time use things that are available with my flatmate.

We don’t have the restriction of entering our home. Yay, we can party all night but we also take care of our Flatmates and make sure that we don’t disturb each other. We don’t have to make deals with the security guard to sneak into the house.

One of the best part of living in shared flat that you can make people clean the room. SimplyGuest providers are awesome and make sure that we don’t have issues with cleaning. They deep clean the house every 2 months

We always have our share of the bathroom time, we always have our timings and nobody disturbs us here. No arguments over bills, SimplyGuest pays it all and no hassle and no need to waste the last Sunday figuring out the finances which we don’t remember.

We all have our bad and good times and flatmates are always there in our good or bad times. We become a family and that’s the best part of it.

On the other hand, I don’t have to really tell anyone about my plans and live my life peacefully.